HLA-B27 stands for Human Leukocyte Antigen B27, an antigen located on the surface of your white blood cells. An HLA-B27 test helps determine the presence of HLA-B27 proteins within blood samples via analysis of these cells. Human leukocyte antigen B27 (HLA-B27) is a protein involved in the immune system. Your body produces this protein, allowing your immune system to identify substances deemed dangerous. The presence of HLA-B27 antigen makes you vulnerable to developing a condition such as juvenile rheumatoid arthritis, autoimmune hepatitis, ankylosing spondylitis, rheumatoid arthritis type II, lupus erythematosus, or Crohn’s disease.
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A negative test indicates that HLA-B27 is not present on your white blood cells. However, keep in mind that a negative result does not mean you do or do not have an autoimmune disorder. You should consider your symptoms, clinical examination and other blood and urine tests when deciding whether or not to seek treatment for an autoimmune disorder.
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The results of the HLA-B27 test are reported as positive or negative, indicating the presence or absence of the antigen in the individual’s blood. A normal result is termed “negative,” indicating the absence of HLA-B27 antigen.
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What does the HLA B27 Test Measure ?
HLA-B27 test can be used along with other blood, urine, or imaging tests to confirm a diagnosis of autoimmune diseases. The test is not confirmatory or a biomarker for disease in an individual but acts as a predisposing factor. The test is vital in establishing the progression and evaluation of diseases associated with the antigen.
Why should I do the HLA B27 Test ?
HLA B27 antigen is a specific type of protein that contributes to immune system dysfunction. The presence of the HLA B27 antigen on the cell surface may result in various autoimmune diseases and disorders. It is also necessary during kidney and bone marrow transplants, where the matching of donor and recipient is crucial for successful organ transplantation.
How is the HLA B27 Test Done ?
The HLA B27 test is a special blood test with no need for fasting before the test. The blood sample can be taken by the phlebotomist at a pathology lab or at home. Aty NABL Certified Maurya Labs the test is done on a PCR machine, which is the best machine for the HLA B27 test. The sample collection takes less than a minute.
What diseases are associated with HLA B27 ?
HLA B27 antigen is a specific type of protein that contributes to immune system dysfunction. The presence of the HLA B27 antigen on the cell surface may result in various autoimmune diseases and disorders. It is also necessary during kidney and bone marrow transplants, where the matching of donor and recipient is crucial for successful organ transplantation.
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Opposite Sadar Hospital, Azad Nagar,
Araria, Bihar - 854311
Mob : +91-92 34 34 4301
Power House Road, Near HP World,
Rajhata, Binodpur, Katihar,
Bihar - 854105
Mob : +91-92 34 34 4301
