Homocysteine is one of the commonest types of amino acids (produced in the body as a by-product of methylation) typically present in very small amounts in all the cells of the body. It is needed in small amounts by the human body to make new proteins. Normally, homocysteine is quickly broken down by Vitamin B12, Vitamin B6 and Vitamin B9 (Folate). A slight increase in the levels of this amino acid could be a sign of deficiency in these Vitamins. This could further lead to various coronary heart diseases, dementia, stroke etc. An elevated level of homocysteine in the blood is responsible for around 10 % of mortality from cardiovascular diseases. A homocysteine test, also known as total homocysteine or plasma total homocysteine, is a simple test ordered by a physician to measure the homocysteine levels in the blood and/or urine.
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Generally, homocysteine breaks down into other substances and a small amount of homocysteine remains in the blood. Some conditions interfere with this mechanism, resulting in high levels of homocysteine in the blood. If the results of the test show high homocysteine levels, it may indicate:
Low levels of Vitamin B6, Vitamin B9 and/or Vitamin B12 in regular diet
A higher risk of cardiovascular diseases
Homocystinuria
An abnormal level of homocysteine does not necessarily imply you should have a medical condition that needs treatment. There are other factors as well that can affect the results:
Homocysteine levels can get higher as you grow old
Men usually have higher levels of homocysteine compared to women
Excessive alcohol intake
Smoking
High use of Vitamin B supplements
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Normal Range – 5 to 15 micromoles per liter (mcmol/L)
Excess > 50mcmol/L
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What does the Homocysteine Test Measure ?
A Homocysteine test measures the homocysteine levels in the blood and/or urine.
It is mostly advised by the doctor for following reasons:
To diagnose deficiencies of Vitamin B6, Vitamin B9 and Vitamin B12 as they are responsible for the metabolism of homocysteine.
For the diagnosis of homocystinuria, a rare inherited disorder that prevents the human body from breaking down certain proteins, leading to serious health issues, especially in childhood.
To monitor the effectiveness of ongoing treatment of heart diseases or stroke
Why should I do the Homocysteine Test ?
This test would be needed if you are facing symptoms of Vitamin B deficiency, such as:
Dizziness
Fatigue
Muscular weakness
Pale skin
Sore tongue and mouth
Diarrhoea
Tingling, numbness and/or burning sensation in feet, hands and arms
Breathlessness
Rapid heart rate
How is the Homocysteine Test Done ?
The Homocysteine test is a simple blood test with no need for fasting before the test. The blood sample can be taken by the phlebotomist at a pathology lab or at home. The test is best done at NABL certified Maurya Labs at affordable proces. The sample collection takes less than a minute.
How often should Homocysteine Test be Done ?
This test could be needed, especially if you are at a high risk of heart disease because of previous heart problems or a family history of heart disease. Excessive levels of homocysteine can build up in the arteries, which may increase your risk of blood clots, heart attack, and stroke.
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Mob : +91-92 34 34 4301
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Rajhata, Binodpur, Katihar,
Bihar - 854105
Mob : +91-92 34 34 4301
